Potassium-sparing diuretic refers to
diuretic drugs that do not promote the secretion of
potassium into the urine. They are used as adjunctive
therapy, together with other drugs, in the treatment of
hypertension and management of congestive heart failure.
Potassium-sparing diuretics do not share any obvious chemical similarities, except for the steroid-structure of the aldosterone antagonists. Those in clinical use include:
- Amiloride
- Triamterene
-
Aldosterone antagonists
- Spironolactone
- Eplerenone
References
- Block JH, Beale JM. "Organic Medicinal and Pharmaceutical Chemistry" 11th edition. Lippincott Williams & Wilkins. 2004.